
{"id":51098,"date":"2024-12-14T13:49:59","date_gmt":"2024-12-14T13:49:59","guid":{"rendered":""},"modified":"2024-12-14T13:49:59","modified_gmt":"2024-12-14T13:49:59","slug":"%d8%aa%d8%b1%d8%ac%d9%85%d9%87-%d9%81%d8%a7%d8%b1%d8%b3%db%8c-%d9%85%d9%82%d8%a7%d9%84%d9%87-51098","status":"publish","type":"product","link":"https:\/\/express24.ir\/d\/product\/%d8%aa%d8%b1%d8%ac%d9%85%d9%87-%d9%81%d8%a7%d8%b1%d8%b3%db%8c-%d9%85%d9%82%d8%a7%d9%84%d9%87-51098\/","title":{"rendered":"\u062a\u0631\u062c\u0645\u0647 \u0641\u0627\u0631\u0633\u06cc \u0645\u0642\u0627\u0644\u0647 \u0627\u0632 Biobanking \u062a\u0627 \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc: \u0633\u0641\u0631 Biobank \u0627\u0633\u062a\u0648\u0646\u06cc"},"content":{"rendered":"<table class=\"table table-striped table-hover\">\n<tbody>\n<tr>\n<td>\u0639\u0646\u0648\u0627\u0646 \u0645\u0642\u0627\u0644\u0647 \u0628\u0647 \u0627\u0646\u06af\u0644\u06cc\u0633\u06cc <\/td>\n<td>From Biobanking to Personalized Medicine: the journey of the Estonian Biobank<\/td>\n<\/tr>\n<tr>\n<td>\u0639\u0646\u0648\u0627\u0646 \u0645\u0642\u0627\u0644\u0647 \u0628\u0647 \u0641\u0627\u0631\u0633\u06cc <\/td>\n<td>\u062a\u0631\u062c\u0645\u0647 \u0641\u0627\u0631\u0633\u06cc \u0645\u0642\u0627\u0644\u0647 \u0627\u0632 Biobanking \u062a\u0627 \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc: \u0633\u0641\u0631 Biobank \u0627\u0633\u062a\u0648\u0646\u06cc<\/td>\n<\/tr>\n<tr>\n<td>\u0646\u0648\u06cc\u0633\u0646\u062f\u06af\u0627\u0646 <\/td>\n<td>  ProfileLili Milani, Maris Alver, Sven Laur, Sulev Reisberg, Toomas Haller,   ProfileOliver Aasmets,   ProfileErik Abner,   ProfileHelene Alavere, Annely Allik,   ProfileTarmo Annilo, Krista Fischer, Georgi Hudjashov,   ProfileMaarja J\u00f5eloo, Mart Kals, Liis Karo-Astover,   ProfileSilva Kasela,   ProfileAnastassia Kolde,   ProfileKristi Krebs,   ProfileKertu Liis Krigul,   ProfileJaanika Kronberg, Karoliina Kruusmaa, Viktorija Kuku\u0161kina,   ProfileKadri K\u00f5iv,   ProfileKelli Lehto, Liis Leitsalu,   ProfileSirje Lind, Laura Birgit Luitva, Kristi L\u00e4ll,   ProfileKreete L\u00fcll, Kristjan Metsalu, Mait Metspalu, Ren\u00e9 M\u00f5ttus,   ProfileMari Nelis, Tiit Nikopensius,   ProfileMiriam Nurm, Margit N\u00f5ukas,   ProfileMarek Oja, Elin Org,   ProfileMarili Palover,   ProfilePriit Palta,   ProfileVasili Pankratov, Kateryna Pantiukh, Natalia Pervjakova, Nat\u00e0lia Pujol-Gualdo,   ProfileAnu Reigo,   ProfileEne Reimann,   ProfileSteven Smit, Diana Sokurova, Nele Taba, Harry-Anton Talvik,   ProfileMaris Teder-Laving, Neeme T\u00f5nisson,   ProfileMariliis Vaht,   ProfileUku Vainik,   ProfileUrmo V\u00f5sa,   ProfileT\u00f5nu Esko, Raivo Kolde, Reedik M\u00e4gi,   ProfileJaak Vilo,   ProfileTriin Laisk,   ProfileAndres Metspalu<\/td>\n<\/tr>\n<tr>\n<td>\u0641\u0631\u0645\u062a \u0645\u0642\u0627\u0644\u0647 \u0627\u0646\u06af\u0644\u06cc\u0633\u06cc <\/td>\n<td>PDF<\/td>\n<\/tr>\n<tr>\n<td>\u0632\u0628\u0627\u0646 \u0645\u0642\u0627\u0644\u0647 \u062a\u062d\u0648\u06cc\u0644\u06cc <\/td>\n<td>\u062a\u0631\u062c\u0645\u0647 \u0641\u0627\u0631\u0633\u06cc<\/td>\n<\/tr>\n<tr>\n<td>\u0641\u0631\u0645\u062a \u0645\u0642\u0627\u0644\u0647 \u062a\u0631\u062c\u0645\u0647 \u0634\u062f\u0647 <\/td>\n<td>\u0628\u0647 \u0635\u0648\u0631\u062a \u0641\u0627\u06cc\u0644 \u0648\u0631\u062f<\/td>\n<\/tr>\n<tr>\n<td>\u0646\u062d\u0648\u0647 \u062a\u062d\u0648\u06cc\u0644 \u062a\u0631\u062c\u0645\u0647 <\/td>\n<td>\u062f\u0648 \u062a\u0627 \u0633\u0647 \u0631\u0648\u0632 \u067e\u0633 \u0627\u0632 \u062b\u0628\u062a \u0633\u0641\u0627\u0631\u0634 (\u0628\u0647 \u0635\u0648\u0631\u062a \u0641\u0627\u06cc\u0644 \u062f\u0627\u0646\u0644\u0648\u062f\u06cc)<\/td>\n<\/tr>\n<tr>\n<td>\u062a\u0639\u062f\u0627\u062f \u0635\u0641\u062d\u0627\u062a<\/td>\n<td>42<\/td>\n<\/tr>\n<tr>\n<td>\u0644\u06cc\u0646\u06a9 \u062f\u0627\u0646\u0644\u0648\u062f \u0631\u0627\u06cc\u06af\u0627\u0646 \u0645\u0642\u0627\u0644\u0647 \u0627\u0646\u06af\u0644\u06cc\u0633\u06cc<\/td>\n<td><a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2024.09.22.24313964v1.full.pdf\">\u062f\u0627\u0646\u0644\u0648\u062f \u0645\u0642\u0627\u0644\u0647<\/a><\/td>\n<\/tr>\n<tr>\n<td>\u062f\u0633\u062a\u0647 \u0628\u0646\u062f\u06cc \u0645\u0648\u0636\u0648\u0639\u0627\u062a  <\/td>\n<td>Genetic and Genomic Medicine<br \/>\n\u062f\u0627\u0631\u0648\u06cc \u0698\u0646\u062a\u06cc\u06a9\u06cc \u0648 \u0698\u0646\u0648\u0645\u06cc<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\r\n<table class=\"table table-striped table-hover table-primary\">\r\n    <tr>\r\n        <td>\u0641\u0631\u0645\u062a \u0627\u0631\u0627\u0626\u0647 \u062a\u0631\u062c\u0645\u0647 \u0645\u0642\u0627\u0644\u0647  <\/td>\r\n        <td>\u062a\u062d\u0648\u06cc\u0644 \u0628\u0647 \u0635\u0648\u0631\u062a \u0641\u0627\u06cc\u0644 \u0648\u0631\u062f<\/td>\r\n    <\/tr>\r\n    <tr>\r\n        <td>\u0632\u0645\u0627\u0646 \u062a\u062d\u0648\u06cc\u0644 \u062a\u0631\u062c\u0645\u0647 \u0645\u0642\u0627\u0644\u0647  <\/td>\r\n        <td>\u0628\u06cc\u0646 2 \u062a\u0627 3 \u0631\u0648\u0632 \u067e\u0633 \u0627\u0632 \u062b\u0628\u062a \u0633\u0641\u0627\u0631\u0634<\/td>\r\n    <\/tr>\r\n\t<tr>\r\n        <td>\u06a9\u06cc\u0641\u06cc\u062a \u062a\u0631\u062c\u0645\u0647  <\/td>\r\n        <td>\u0628\u0633\u06cc\u0627\u0631 \u0628\u0627\u0644\u0627. \u0645\u0642\u0627\u0644\u0647 \u0641\u0642\u0637 \u062a\u0648\u0633\u0637 \u0645\u062a\u0631\u062c\u0645\u06cc\u0646 \u0628\u0627 \u0645\u062f\u0631\u06a9 \u062f\u0627\u0646\u0634\u06af\u0627\u0647\u06cc \u0645\u062a\u0631\u062c\u0645\u06cc \u062a\u0631\u062c\u0645\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/td>\r\n    <\/tr>\r\n\t\t<tr>\r\n        <td>\u062c\u062f\u0627\u0648\u0644 \u0648 \u0641\u0631\u0645\u0648\u0644 \u0647\u0627  <\/td>\r\n        <td>\u06a9\u0644\u06cc\u0647 \u062c\u062f\u0627\u0648\u0644 \u0648 \u0641\u0631\u0645\u0648\u0644 \u0647\u0627 \u0646\u06cc\u0632 \u062f\u0631 \u0641\u0627\u06cc\u0644 \u062a\u062d\u0648\u06cc\u0644\u06cc \u0648\u0631\u062f \u062f\u0631\u062c \u0645\u06cc\u200c\u0634\u0648\u0646\u062f.<\/td>\r\n    <\/tr>\r\n<\/table>\r\n\r\n\n<h2>\u0686\u06a9\u06cc\u062f\u0647<\/h2>\n<p style=\"direction:ltr;\">Large biobanks have set a new standard for research and innovation in human genomics and implementation of personalised medicine. The Estonian Biobank was founded a quarter of a century ago, and its biological specimens, clinical, health, omics, and lifestyle data have been included in over 800 publications to date. What makes the biobank unique internationally is its translational focus, with active efforts to conduct clinical studies based on genetic findings, and to explore the effects of return of results on participants. In this review we provide an overview of the Estonian Biobank, highlight its strengths for studying the effects of genetic variation and quantitative phenotypes on health-related traits, development of methods and frameworks for bringing genomics into the clinic, and its role as a driving force for implementing personalized medicine on a national level and beyond.<\/p>\n<h2>\u0686\u06a9\u06cc\u062f\u0647 \u0628\u0647 \u0641\u0627\u0631\u0633\u06cc (\u062a\u0631\u062c\u0645\u0647 \u0645\u0627\u0634\u06cc\u0646\u06cc)<\/h2>\n<p>Biobanks \u0628\u0632\u0631\u06af \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f \u062c\u062f\u06cc\u062f\u06cc \u0631\u0627 \u0628\u0631\u0627\u06cc \u062a\u062d\u0642\u06cc\u0642 \u0648 \u0646\u0648\u0622\u0648\u0631\u06cc \u062f\u0631 \u0698\u0646\u0648\u0645\u06cc\u06a9 \u0627\u0646\u0633\u0627\u0646\u06cc \u0648 \u0627\u062c\u0631\u0627\u06cc \u0637\u0628 \u0634\u062e\u0635\u06cc \u062a\u0639\u06cc\u06cc\u0646 \u06a9\u0631\u062f\u0647 \u0627\u0633\u062a.Biobank \u0627\u0633\u062a\u0648\u0646\u06cc \u06cc\u06a9 \u0686\u0647\u0627\u0631\u0645 \u0642\u0631\u0646 \u0642\u0628\u0644 \u062a\u0623\u0633\u06cc\u0633 \u0634\u062f \u0648 \u0646\u0645\u0648\u0646\u0647 \u0647\u0627\u06cc \u0628\u06cc\u0648\u0644\u0648\u0698\u06cc\u06a9\u06cc \u0622\u0646 \u060c \u0628\u0627\u0644\u06cc\u0646\u06cc \u060c \u0628\u0647\u062f\u0627\u0634\u062a \u060c OMICS \u0648 \u062f\u0627\u062f\u0647 \u0647\u0627\u06cc \u0634\u06cc\u0648\u0647 \u0632\u0646\u062f\u06af\u06cc \u062a\u0627 \u0628\u0647 \u0627\u0645\u0631\u0648\u0632 \u062f\u0631 \u0628\u06cc\u0634 \u0627\u0632 800 \u0646\u0634\u0631\u06cc\u0647 \u06af\u0646\u062c\u0627\u0646\u062f\u0647 \u0634\u062f\u0647 \u0627\u0633\u062a.\u0622\u0646\u0686\u0647 Biobank \u0631\u0627 \u062f\u0631 \u0633\u0637\u062d \u0628\u06cc\u0646 \u0627\u0644\u0645\u0644\u0644\u06cc \u0645\u0646\u062d\u0635\u0631 \u0628\u0647 \u0641\u0631\u062f \u0645\u06cc \u06a9\u0646\u062f \u060c \u062a\u0645\u0631\u06a9\u0632 \u062a\u0631\u062c\u0645\u0647 \u0622\u0646 \u0627\u0633\u062a \u060c \u0628\u0627 \u062a\u0644\u0627\u0634 \u0647\u0627\u06cc \u0641\u0639\u0627\u0644 \u0628\u0631\u0627\u06cc \u0627\u0646\u062c\u0627\u0645 \u0645\u0637\u0627\u0644\u0639\u0627\u062a \u0628\u0627\u0644\u06cc\u0646\u06cc \u0628\u0631 \u0627\u0633\u0627\u0633 \u06cc\u0627\u0641\u062a\u0647 \u0647\u0627\u06cc \u0698\u0646\u062a\u06cc\u06a9\u06cc \u0648 \u0628\u0631\u0631\u0633\u06cc \u062a\u0623\u062b\u06cc\u0631 \u0628\u0627\u0632\u06af\u0634\u062a \u0646\u062a\u0627\u06cc\u062c \u0628\u0631 \u0634\u0631\u06a9\u062a \u06a9\u0646\u0646\u062f\u06af\u0627\u0646.\u062f\u0631 \u0627\u06cc\u0646 \u0628\u0631\u0631\u0633\u06cc \u060c \u0645\u0627 \u06cc\u06a9 \u0645\u0631\u0648\u0631 \u06a9\u0644\u06cc \u0627\u0632 Biobank \u0627\u0633\u062a\u0648\u0646\u06cc \u0627\u0631\u0627\u0626\u0647 \u0645\u06cc \u062f\u0647\u06cc\u0645 \u060c \u0646\u0642\u0627\u0637 \u0642\u0648\u062a \u0622\u0646 \u0631\u0627 \u0628\u0631\u0627\u06cc \u0645\u0637\u0627\u0644\u0639\u0647 \u0627\u062b\u0631\u0627\u062a \u062a\u0646\u0648\u0639 \u0698\u0646\u062a\u06cc\u06a9\u06cc \u0648 \u0641\u0646\u0648\u062a\u06cc\u067e \u0647\u0627\u06cc \u06a9\u0645\u06cc \u0628\u0631 \u0631\u0648\u06cc \u0635\u0641\u0627\u062a \u0645\u0631\u062a\u0628\u0637 \u0628\u0627 \u0633\u0644\u0627\u0645\u062a\u06cc \u060c \u062a\u0648\u0633\u0639\u0647 \u0631\u0648\u0634 \u0647\u0627 \u0648 \u0686\u0627\u0631\u0686\u0648\u0628 \u0647\u0627 \u0628\u0631\u0627\u06cc \u0648\u0627\u0631\u062f \u06a9\u0631\u062f\u0646 \u0698\u0646\u0648\u0645\u06cc\u06a9 \u0628\u0647 \u06a9\u0644\u06cc\u0646\u06cc\u06a9 \u0648 \u0646\u0642\u0634 \u0622\u0646 \u0628\u0647 \u0639\u0646\u0648\u0627\u0646 \u0646\u06cc\u0631\u0648\u06cc \u0645\u062d\u0631\u06a9 \u0627\u0631\u0627\u0626\u0647 \u0645\u06cc \u062f\u0647\u06cc\u0645.\u0628\u0631\u0627\u06cc \u0627\u062c\u0631\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc \u062f\u0631 \u0633\u0637\u062d \u0645\u0644\u06cc \u0648 \u0641\u0631\u0627\u062a\u0631 \u0627\u0632 \u0622\u0646.<\/p>\n\r\n<table class=\"table table-striped table-hover table-primary\">\r\n    <tr>\r\n        <td>\u0641\u0631\u0645\u062a \u0627\u0631\u0627\u0626\u0647 \u062a\u0631\u062c\u0645\u0647 \u0645\u0642\u0627\u0644\u0647  <\/td>\r\n        <td>\u062a\u062d\u0648\u06cc\u0644 \u0628\u0647 \u0635\u0648\u0631\u062a \u0641\u0627\u06cc\u0644 \u0648\u0631\u062f<\/td>\r\n    <\/tr>\r\n    <tr>\r\n        <td>\u0632\u0645\u0627\u0646 \u062a\u062d\u0648\u06cc\u0644 \u062a\u0631\u062c\u0645\u0647 \u0645\u0642\u0627\u0644\u0647  <\/td>\r\n        <td>\u0628\u06cc\u0646 2 \u062a\u0627 3 \u0631\u0648\u0632 \u067e\u0633 \u0627\u0632 \u062b\u0628\u062a \u0633\u0641\u0627\u0631\u0634<\/td>\r\n    <\/tr>\r\n\t<tr>\r\n        <td>\u06a9\u06cc\u0641\u06cc\u062a \u062a\u0631\u062c\u0645\u0647  <\/td>\r\n        <td>\u0628\u0633\u06cc\u0627\u0631 \u0628\u0627\u0644\u0627. \u0645\u0642\u0627\u0644\u0647 \u0641\u0642\u0637 \u062a\u0648\u0633\u0637 \u0645\u062a\u0631\u062c\u0645\u06cc\u0646 \u0628\u0627 \u0645\u062f\u0631\u06a9 \u062f\u0627\u0646\u0634\u06af\u0627\u0647\u06cc \u0645\u062a\u0631\u062c\u0645\u06cc \u062a\u0631\u062c\u0645\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/td>\r\n    <\/tr>\r\n\t\t<tr>\r\n        <td>\u062c\u062f\u0627\u0648\u0644 \u0648 \u0641\u0631\u0645\u0648\u0644 \u0647\u0627  <\/td>\r\n        <td>\u06a9\u0644\u06cc\u0647 \u062c\u062f\u0627\u0648\u0644 \u0648 \u0641\u0631\u0645\u0648\u0644 \u0647\u0627 \u0646\u06cc\u0632 \u062f\u0631 \u0641\u0627\u06cc\u0644 \u062a\u062d\u0648\u06cc\u0644\u06cc \u0648\u0631\u062f \u062f\u0631\u062c \u0645\u06cc\u200c\u0634\u0648\u0646\u062f.<\/td>\r\n    <\/tr>\r\n<\/table>\r\n\r\n\n","protected":false},"excerpt":{"rendered":"<p>\u0639\u0646\u0648\u0627\u0646 \u0645\u0642\u0627\u0644\u0647 \u0628\u0647 \u0627\u0646\u06af\u0644\u06cc\u0633\u06cc From Biobanking to Personalized Medicine: the journey of the Estonian Biobank \u0639\u0646\u0648\u0627\u0646 \u0645\u0642\u0627\u0644\u0647 \u0628\u0647 \u0641\u0627\u0631\u0633\u06cc \u062a\u0631\u062c\u0645\u0647 [&hellip;]<\/p>\n","protected":false},"featured_media":27,"comment_status":"open","ping_status":"open","template":"","meta":{"pmpro_default_level":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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