{"id":26356,"date":"2024-02-25T14:24:36","date_gmt":"2024-02-25T15:24:36","guid":{"rendered":"https:\/\/express24.ir\/d\/product\/%d9%85%d9%82%d8%a7%d9%84%d9%87-%d8%a2%d9%85%d9%88%d8%b2%d8%b4-%d9%88-%d9%85%d9%82%d8%a7%db%8c%d8%b3%d9%87-%d8%b1%d9%88%d8%b4%d9%87%d8%a7%db%8c-nnu-net-%d9%88-deepmedic-%d8%a8%d8%b1%d8%a7\/"},"modified":"2024-02-25T14:24:37","modified_gmt":"2024-02-25T15:24:37","slug":"%d9%85%d9%82%d8%a7%d9%84%d9%87-%d8%a2%d9%85%d9%88%d8%b2%d8%b4-%d9%88-%d9%85%d9%82%d8%a7%db%8c%d8%b3%d9%87-%d8%b1%d9%88%d8%b4%d9%87%d8%a7%db%8c-nnu-net-%d9%88-deepmedic-%d8%a8%d8%b1%d8%a7","status":"publish","type":"product","link":"https:\/\/express24.ir\/d\/product\/%d9%85%d9%82%d8%a7%d9%84%d9%87-%d8%a2%d9%85%d9%88%d8%b2%d8%b4-%d9%88-%d9%85%d9%82%d8%a7%db%8c%d8%b3%d9%87-%d8%b1%d9%88%d8%b4%d9%87%d8%a7%db%8c-nnu-net-%d9%88-deepmedic-%d8%a8%d8%b1%d8%a7\/","title":{"rendered":"\u0645\u0642\u0627\u0644\u0647 \u0622\u0645\u0648\u0632\u0634 \u0648 \u0645\u0642\u0627\u06cc\u0633\u0647 \u0631\u0648\u0634\u200c\u0647\u0627\u06cc nnU-Net \u0648 DeepMedic \u0628\u0631\u0627\u06cc \u062a\u0642\u0633\u06cc\u0645\u200c\u0628\u0646\u062f\u06cc \u062e\u0648\u062f\u06a9\u0627\u0631 \u062a\u0648\u0645\u0648\u0631\u0647\u0627\u06cc \u0645\u063a\u0632\u06cc \u06a9\u0648\u062f\u06a9\u0627\u0646"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n
\u0639\u0646\u0648\u0627\u0646 \u0645\u0642\u0627\u0644\u0647 \u0628\u0647 \u0627\u0646\u06af\u0644\u06cc\u0633\u06cc <\/td>\nTraining and Comparison of nnU-Net and DeepMedic Methods for Autosegmentation of Pediatric Brain Tumors<\/td>\n<\/tr>\n
\u0639\u0646\u0648\u0627\u0646 \u0645\u0642\u0627\u0644\u0647 \u0628\u0647 \u0641\u0627\u0631\u0633\u06cc <\/td>\n\u0645\u0642\u0627\u0644\u0647 \u0622\u0645\u0648\u0632\u0634 \u0648 \u0645\u0642\u0627\u06cc\u0633\u0647 \u0631\u0648\u0634\u0647\u0627\u06cc NNU-NET \u0648 DeepMedic \u0628\u0631\u0627\u06cc \u062e\u0648\u062f\u06a9\u0627\u0631\u0633\u0627\u0632\u06cc \u062a\u0648\u0645\u0648\u0631\u0647\u0627\u06cc \u0645\u063a\u0632\u06cc \u06a9\u0648\u062f\u06a9\u0627\u0646<\/td>\n<\/tr>\n
\u0646\u0648\u06cc\u0633\u0646\u062f\u06af\u0627\u0646 <\/td>\nArastoo Vossough, Nastaran Khalili, Ariana M. Familiar, Deep Gandhi, Karthik Viswanathan, Wenxin Tu, Debanjan Haldar, Sina Bagheri, Hannah Anderson, Shuvanjan Haldar, Phillip B. Storm, Adam Resnick, Jeffrey B. Ware, Ali Nabavizadeh, Anahita Fathi Kazerooni<\/td>\n<\/tr>\n
\u0632\u0628\u0627\u0646 \u0645\u0642\u0627\u0644\u0647 <\/td>\n\u0627\u0646\u06af\u0644\u06cc\u0633\u06cc<\/td>\n<\/tr>\n
\u0641\u0631\u0645\u062a \u0645\u0642\u0627\u0644\u0647: <\/td>\nPDF<\/td>\n<\/tr>\n
\u062a\u0639\u062f\u0627\u062f \u0635\u0641\u062d\u0627\u062a<\/td>\n33<\/td>\n<\/tr>\n
\u062f\u0633\u062a\u0647 \u0628\u0646\u062f\u06cc \u0645\u0648\u0636\u0648\u0639\u0627\u062a <\/td>\nImage and Video Processing,Computer Vision and Pattern Recognition,Machine Learning,Medical Physics,\u067e\u0631\u062f\u0627\u0632\u0634 \u062a\u0635\u0648\u06cc\u0631 \u0648 \u0641\u06cc\u0644\u0645 , \u062f\u06cc\u062f \u0631\u0627\u06cc\u0627\u0646\u0647 \u0648 \u062a\u0634\u062e\u06cc\u0635 \u0627\u0644\u06af\u0648\u06cc , \u06cc\u0627\u062f\u06af\u06cc\u0631\u06cc \u0645\u0627\u0634\u06cc\u0646 , \u0641\u06cc\u0632\u06cc\u06a9 \u067e\u0632\u0634\u06a9\u06cc ,<\/td>\n<\/tr>\n
\u062a\u0648\u0636\u06cc\u062d\u0627\u062a <\/td>\nSubmitted 16 January, 2024; originally announced January 2024.<\/td>\n<\/tr>\n
\u062a\u0648\u0636\u06cc\u062d\u0627\u062a \u0628\u0647 \u0641\u0627\u0631\u0633\u06cc <\/td>\n16 \u0698\u0627\u0646\u0648\u06cc\u0647 2024 \u0627\u0631\u0633\u0627\u0644 \u0634\u062f.\u062f\u0631 \u0627\u0628\u062a\u062f\u0627 \u0698\u0627\u0646\u0648\u06cc\u0647 2024 \u0627\u0639\u0644\u0627\u0645 \u0634\u062f.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u0686\u06a9\u06cc\u062f\u0647<\/h2>\n

Brain tumors are the most common solid tumors and the leading cause of cancer-related death among children. Tumor segmentation is essential in surgical and treatment planning, and response assessment and monitoring. However, manual segmentation is time-consuming and has high inter-operator variability, underscoring the need for more efficient methods. We compared two deep learning-based 3D segmentation models, DeepMedic and nnU-Net, after training with pediatric-specific multi-institutional brain tumor data using based on multi-parametric MRI scans.Multi-parametric preoperative MRI scans of 339 pediatric patients (n=293 internal and n=46 external cohorts) with a variety of tumor subtypes, were preprocessed and manually segmented into four tumor subregions, i.e., enhancing tumor (ET), non-enhancing tumor (NET), cystic components (CC), and peritumoral edema (ED). After training, performance of the two models on internal and external test sets was evaluated using Dice scores, sensitivity, and Hausdorff distance with reference to ground truth manual segmentations. Dice score for nnU-Net internal test sets was (mean +\/- SD (median)) 0.9+\/-0.07 (0.94) for WT, 0.77+\/-0.29 for ET, 0.66+\/-0.32 for NET, 0.71+\/-0.33 for CC, and 0.71+\/-0.40 for ED, respectively. For DeepMedic the Dice scores were 0.82+\/-0.16 for WT, 0.66+\/-0.32 for ET, 0.48+\/-0.27, for NET, 0.48+\/-0.36 for CC, and 0.19+\/-0.33 for ED, respectively. Dice scores were significantly higher for nnU-Net (p<=0.01). External validation of the trained nnU-Net model on the multi-institutional BraTS-PEDs 2023 dataset revealed high generalization capability in segmentation of whole tumor and tumor core with Dice scores of 0.87+\/-0.13 (0.91) and 0.83+\/-0.18 (0.89), respectively. Pediatric-specific data trained nnU-Net model is superior to DeepMedic for whole tumor and subregion segmentation of pediatric brain tumors.<\/p>\n

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\u0628\u0631\u0627\u06cc WT \u060c 0.66 +\/- 0.32 \u0628\u0631\u0627\u06cc ET \u060c 0.48 +\/- 0.27 \u060c \u0628\u0631\u0627\u06cc \u062e\u0627\u0644\u0635 \u060c 0.48 +\/- 0.36 \u0628\u0631\u0627\u06cc CC \u0648 0.19 +\/- 0.33 \u0628\u0631\u0627\u06cc ED \u0628\u0648\u062f.\u0646\u0645\u0631\u0627\u062a \u062a\u0627\u0633 \u0628\u0631\u0627\u06cc NNU-NET \u0628\u0647 \u0637\u0648\u0631 \u0642\u0627\u0628\u0644 \u062a\u0648\u062c\u0647\u06cc \u0628\u0627\u0644\u0627\u062a\u0631 \u0628\u0648\u062f (P <0.01).\u0627\u0639\u062a\u0628\u0627\u0631 \u0633\u0646\u062c\u06cc \u062e\u0627\u0631\u062c\u06cc \u0645\u062f\u0644 NNU-NET \u0622\u0645\u0648\u0632\u0634 \u062f\u06cc\u062f\u0647 \u062f\u0631 \u0645\u062c\u0645\u0648\u0639\u0647 \u062f\u0627\u062f\u0647 \u0647\u0627\u06cc \u0686\u0646\u062f \u062c\u0627\u0646\u0628\u0647 BRATS-PEDS 2023 \u062a\u0648\u0627\u0646\u0627\u06cc\u06cc \u062a\u0639\u0645\u06cc\u0645 \u0628\u0627\u0644\u0627 \u062f\u0631 \u062a\u0642\u0633\u06cc\u0645 \u0647\u0633\u062a\u0647 \u06a9\u0644 \u062a\u0648\u0645\u0648\u0631 \u0648 \u062a\u0648\u0645\u0648\u0631 \u0628\u0627 \u0646\u0645\u0631\u0627\u062a \u062a\u0627\u0633 0.87 +\/- 0.13 (0.91) \u0648 0.18 0.18 (0.18 0.18 (0.18) \u0631\u0627 \u0646\u0634\u0627\u0646 \u062f\u0627\u062f.0.89) \u060c \u0628\u0647 \u062a\u0631\u062a\u06cc\u0628.\u062f\u0627\u062f\u0647 \u0647\u0627\u06cc \u062e\u0627\u0635 \u06a9\u0648\u062f\u06a9\u0627\u0646 \u0622\u0645\u0648\u0632\u0634 \u062f\u0627\u062f\u0647 \u0634\u062f\u0647 \u0645\u062f\u0644 NNU-NET \u0628\u0631\u0627\u06cc \u062a\u0642\u0633\u06cc\u0645 \u06a9\u0627\u0645\u0644 \u062a\u0648\u0645\u0648\u0631 \u0648 \u0632\u06cc\u0631 \u0645\u0646\u0637\u0642\u0647 \u062a\u0648\u0645\u0648\u0631\u0647\u0627\u06cc \u0645\u063a\u0632\u06cc \u06a9\u0648\u062f\u06a9\u0627\u0646 \u0628\u0631\u062a\u0631 \u0627\u0632 DeepMedic \u0627\u0633\u062a.\n\n\n\n\n\n[sc name=\"paperTranslation2\"][\/sc]\n<\/p>\n","protected":false},"excerpt":{"rendered":"

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